Our highly effective, fast-acting Retinol+ Emulsion 0.3 (30g) formula combines Retinol of botanical origin with a proprietary blend of Bakuchiol, other powerful botanical boosters, antioxidants, and Extremozymes® to help reduce the appearance of fine lines and deep wrinkles while evening skin tone and texture for a smooth, radiant complexion. All iS Clinical products are non-systemic, this means they do not penetrate the bloodstream or other organs such as the uterus and breasts. Therefore, all our products are safe to use during pregnancy and breast feeding which includes all products containing Retinol.